产品货号：
Z29355
中文名称：
ULK3抗体
英文名称：
Anti-ULK3 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ULK3 Antibody |
| 指标别名 | unc-51 like kinase 3;ULK3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | ULK3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from human ULK3 |
| 计算分子量 | 53KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy.In search of potential homologues to Drosophila and human Fu,people have cloned human serine/threonine kinase ULK3 and assessed its ability to regulate GLI transcription factors,mediators of SHH signaling.And ULK3 enhances endogenous and over-expressed GLI1 and GLI2 transcriptional activity in cultured cells,as assessed by GLI-luciferase reporter assay.Besides that,ULK3 alters subcellular localization of GLI1,as assessed by immunofluorescent staining and immunoblotting assays.It is showed that ULK3 is an autophosphorylated kinase and phosphorylates GLI proteins in vitro.Also,ULK3 catalytical activity is crucial for its function in SHH pathway.It is demonstrated that ULK3 is widely expressed and its expression is higher in a number of tissues where Shh signaling is known to be active.The data suggest that serine/threonine kinase ULK3 is involved in the SHH pathway as a positive regulator of GLI proteins. |
| Uniprot ID | Q6PHR2 |
| 基因名全称 | Serine/threonine-protein kinase ULK3 |
| 蛋白名全称 | Serine/threonine-protein kinase ULK3 |
| 推荐稀释比 | WB 1:500～1:2000 IHC 1:100～1:300 ELISA 1:20000 |
相关搜索：ULK3抗体，ULK3多抗，Anti-ULK3 Antibody